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| Catalog Number | orb570282 |
|---|---|
| Category | Proteins |
| Description | Human IL-12 R beta 1, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 540 (Accession # P42701-1). |
| Target | IL-12 R beta 1 |
| Conjugation | Unconjugated |
| Tag | C-Fc |
| Reactivity | Human |
| Form/Appearance | Powder |
| Buffer/Preservatives | PBS, pH 7.4 |
| Purity | 90% |
| UniProt ID | P42701 |
| MW | 83.5 kDa |
| Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 83.5 kDa. The protein migrates as 95-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expression System | HEK293 |
| Endotoxins | 1.0 EU per μg |
| Expression Region | Cys 24 - Glu 540 |
| Storage | -20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower |
| Research Area | Disease Biomarkers |
| Note | For research use only |

Human IL-12 R beta 1, Fc Tag (Cat. No. orb570282) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human IL-12B & IL-12A Heterodimer Protein, His Tag & Flag Tag with an affinity constant of 2.06 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
> 95% by SDS-PAGE. | |
Recombinant Human IL-12RB1/IL-12 R beta 1/IL-12RB Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Cys24-Glu540) of human IL-12RB1/IL-12 R beta 1/IL-12RB (Accession #P42701) fused with an Fc tag at the C-terminus. |
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