HPGDS inhibitor 1

SKU: orb1307407

Description

HPGDS inhibitor 1 is a potent and selective small molecule targeting Hematopoietic Prostaglandin D Synthase, exhibiting an IC50 of 0.7 nM. This compound is a valuable research tool for investigating allergic inflammation, mast cell function, and D-prostanoid receptor signaling in both cellular and animal models of disease.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	1033836-12-2
MW	381.37
Purity	99.62%
Formula	C₁₉H₁₉F₄N₃O
SMILES	Fc1cccc(c1)-c1ccc(cn1)C(=O)NC1CCN(CC(F)(F)F)CC1
Target	PGE Synthase
Solubility	10% DMSO+90% Corn Oil:2.5 mg/mL (6.56 mM);DMSO:55 mg/mL (144.22 mM)

Bioactivity

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Target IC50	HPGDS:0.7 nM.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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asthma, HPGDS inhibitor1, HPGDS inhibitor-1, HPGDS-inhibitor-1, hPGDS, HPGDS, HPGDS inhibitor 1, Inhibitor, inhibit, orally, PGE Synthase, PGE synthase, PGD2, PGESynthase, Prostaglandin E synthase

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Compound Identifiers

PubChem CID

24991044 ↗

Key Properties

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No computed properties available.

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