HIV Integrase Protein Inhibitor(1)

SKU: orb2694202

Description

HIV encodes an effective inhibitor peptide of integrase (IN), a peptide composed of six amino acids, which is responsible for integrating HIV DNA into the human genome. HIV Integrate Protein Inhibitor can inhibit IN mediated 3 'processing and integration, with an IC of 2 µ M. This peptide also has activity against IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus, and Moroni mouse leukemia virus. It was also found that it can inhibit the decomposition reaction, indicating that this hexapeptide acts at or near the catalytic site of IN.

Research Area

Infectious Disease & Virology; Pharmacology & Drug Discovery

Key Properties

• Target: HIV
• CAS Number: 172546-75-7
• MW: 906.1
• Purity: ≥95%
• Formula: C₄₆H₅₅N₁₁O₇S
• Protein Sequence: HCKFWW

Storage & Handling

• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

HIV