Integrase-LEDGF/p75 allosteric inhibitor 1

SKU: orb1685943

Description

Integrase-LEDGF/p75 allosteric inhibitor 1 is an orally bioavailable small molecule that disrupts the HIV-1 IN-LEDGF/p75 protein-protein interaction. It potently blocks viral DNA integration, exhibiting antiviral activity with an EC50 of 3.9 nM against HIV-1 NL432 in cell-based assays, making it a valuable tool for studying lentiviral integration mechanisms.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 1431738-14-5
• MW: 579.75
• Formula: C₃₃H₄₁NO₆S
• SMILES: C(OC(C)(C)C)(C(O)=O)C1=C(C(C)=C(C(NS(C)(=O)=O)=C1C)C2=CC(C)=C(C)C=C2)C=3C(C)=C4C(=CC3)OCCC4
• Target: HIV Protease,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

86575523