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| Catalog Number | orb1951870 |
|---|---|
| Category | Antibodies |
| Description | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Clonality | Recombinant |
| Species/Host | Rabbit |
| Isotype | Rabbit IgG |
| Conjugation | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human Histone H3 (acetyl K56) |
| UniProt ID | P68431 |
| Tested applications | ICC, IHC, WB |
| Dilution range | WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
| Antibody Type | Recombinant Antibody |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Alternative names | H3/a; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3 Read more... |
| Note | For research use only |
![Histone H3 (acetyl K56) Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951870_1.png)
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
![Histone H3 (acetyl K56) Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951870_2.png)
Immunofluorescent analysis of Hela cells, using Histone H3 (acetyl K56) Antibody.
![Histone H3 (acetyl K56) Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951870_3.png)
Immunohistochemical analysis of paraffin-embedded human colon, using Histone H3 (acetyl K56) Antibody.
![Histone H3 (acetyl K56) Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1951870_4.png)
Western blot analysis of Histone H3 (acetyl K56) expression in C6 cell lysate, treated with TSA.
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