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Hepln-13

SKU: orb1305328

Description

Hepln-13

Research Area

Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number64369-13-7
MW325.2
Purity99.83% (May vary between batches)
FormulaC17H13BrN2
SMILESBrc1ccc(cc1)C1Nc2cccc3cccc(N1)c23
Targetc-Met/HGFR,Others,Serine Protease
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.15 mM);DMSO:60 mg/mL (184.5 mM)

Bioactivity

Target IC50
Hepsin:0.33 μM
In Vivo
HepIn-13 displays dose-dependent inhibition of Hepsin overexpression-relevant prostate cancer phenotypes in LPB-Tag/PB-Hepsin mice and blocks prostate cancer metastasis in this animal model.
In Vitro
Hepln-13 (10 μM; 2 hours; 293 cells) inhibits cleavage.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

potent, phenotypes, prostate, Inhibitor, hepsin, Hepln 13, Hepln13, Hepln-13, HGFR, non-toxic, inhibit, overexpression-relevant, orally, cMet/HGFR, c-Met, cMet, cancer

Similar Products

  • Hepln-13 [orb1217771]

    >98% (HPLC)

    64369-13-7

    325.2

    C17H13BrN2

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
2 mg
$ 90.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 130.00
10 mg
$ 170.00
25 mg
$ 300.00
50 mg
$ 430.00
100 mg
$ 580.00
200 mg
$ 780.00
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