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Hepln-13

SKU: orb1217771

Description

Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.

Images & Validation

Key Properties

CAS Number64369-13-7
MW325.2
Purity>98% (HPLC)
FormulaC17H13BrN2
SMILESBrc1ccc(C(N2)Nc3cccc4cccc2c34)cc1
Targetc-Met/HGFR
SolubilityDMSO:60 mg/mL (184.50 mM; Need ultrasonic)

Bioactivity

In Vivo
HepIn-13 displays dose dependent inhibition of Hepsin overexpression-relevant prostate cancer phenotypes and blocks prostate cancer metastasis.
In Vitro
Hepln-13 (10 μM; 2 hours; 293 cells) inhibits cleavage. Western blot analysis. Cell line: 293 cells. Concentration: 10 μM. Incubation time: 2 hours. Result: Inhibited cleavage.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Hepln 13 | Hepln13

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  • Hepln-13 [orb1305328]

    99.83% (May vary between batches)

    64369-13-7

    325.2

    C17H13BrN2

    1 ml x 10 mM (in DMSO), 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 2 mg
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Protocol Information

Available Sizes

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5 mg
$ 220.00
10 mg
$ 350.00
25 mg
$ 670.00
50 mg
$ 990.00
100 mg
$ 1,380.00
500 mg
$ 2,810.00