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Catalog Number | orb1951357 |
---|---|
Category | Antibodies |
Description | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. |
Target | HDAC4 |
Clonality | Recombinant |
Species/Host | Rabbit |
Isotype | Rabbit IgG |
Conjugation | Unconjugated |
Reactivity | Human |
Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Immunogen | A synthesized peptide derived from human HDAC4 |
UniProt ID | P56524 |
Tested applications | ICC, WB |
Dilution range | WB 1:1000~1:2000 ICC/IF 1:50~1:200 |
Antibody Type | Recombinant Antibody |
Clone Number | 2.00E+13 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Alternative names | Histone deacetylase 4; HD4; HDAC4; AHO3; BDMR; |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
All Lanes: HDAC4 Antibody at 1/500 dilution. Lane 1: Hela lysate. Proteins at 20 ug per lane, Secondary: Goat Anti-Rabbit IgG (HRP) at 1/20000 dilution. Predicted band size: 140 kDa, Observed band size: 140 kDa.