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Catalog Number | orb1298633 |
---|---|
Category | Small Molecules |
Description | HALOFUGINONE LACTATE |
Purity | 99.02% |
MW | 504.8 |
Biological Activity | HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity |
CAS Number | 82186-71-8 |
Formula | C19H23BrClN3O6 |
SMILES | CC(O)C(O)=O.O=C1N(CC(C[C@@H]2NCCC[C@H]2O)=O)C=NC3=C1C=C(Cl)C(Br)=C3 |
Storage | -20°C |
Note | For research use only |
> 98% (HPLC) | |
82186-71-8 | |
504.8 | |
C19H23BrClN3O6 |