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HA130

SKU: orb1305222

Description

HA130 is a potent and selective small molecule inhibitor of autotaxin (ATX), an enzyme critical for lysophosphatidic acid (LPA) production. It is a valuable research tool for investigating the ATX-LPA signaling axis in both cellular assays and animal models of fibrosis, cancer, and inflammation.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1229652-21-4
MW463.29
Purity>99.99% (May vary between batches)
FormulaC24H19BFNO5S
SMILESOB(O)c1cccc(COc2ccc(\C=C3/SC(=O)N(Cc4ccc(F)cc4)C3=O)cc2)c1
TargetPDE
SolubilityDMSO:46.33 mg/mL (100 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.32 mM)

Bioactivity

Target IC50
ATX:28 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, HA130, HA-130, HA 130, inhibit, ATX (autotaxin), phosphodiesterase, Phosphodiesterase (PDE)

Similar Products

  • HA-130 [orb1226728]

    >98% (HPLC)

    1229652-21-4

    463.2858

    C24H19BFNO5S

    2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 25 mg, 500 mg, 1 g, 200 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 80.00
5 mg
$ 100.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 130.00
25 mg
$ 190.00
50 mg
$ 290.00
100 mg
$ 410.00
200 mg
$ 600.00
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