GZD856

SKU: orb1909901

Description

GZD856 is a novel and orally bioavailable PDGFRα/β inhibitor with IC50s of 68.6 and 136.6 nM, respectively. Anti-lung cancer activities. Also a Bcr-AblT315I inhibitor with IC50s of 19.9 and 15.4 nM for Bcr-Abl and T315I mutant.

Key Properties

• CAS Number: 1257628-64-0
• MW: 532.559496164322
• Purity: >98%
• Formula: C₂₉H₂₇F₃N₆O
• SMILES: FC(C1C=C(C=CC=1CN1CCN(C)CC1)NC(C1C=CC(C)=C(C#CC2C=NC3=CC=NN3C=2)C=1)=O)(F)F

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only