GZD856 formic

SKU: orb1685952

Description

GZD856 formic is a potent, orally bioavailable small molecule inhibitor targeting PDGFRα/β and Bcr-Abl, including the resistant T315I mutant. It demonstrates significant antitumor efficacy in preclinical models, making it a valuable research tool for studying tyrosine kinase-driven cancers in both in vitro and in vivo settings.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2804039-78-7
• MW: 578.58
• Formula: C₃₀H₂₉F₃N₆O₃
• SMILES: C(O)=O.C(C1=C(C(F)(F)F)C=C(NC(=O)C2=CC(C#CC3=CN4C(N=C3)=CC=N4)=C(C)C=C2)C=C1)N5CCN(C)CC5
• Target: Others,PDGFR,Apoptosis,Bcr-Abl

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155981976