GSK3α/β(Phospho-Tyr216/Tyr279) Rabbit mAb [KD Validated]

• Catalog Number: orb1727717
• Category: Antibodies
• Description: GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
• Species/Host: Rabbit
• Clonality: Recombinant
• Tested applications: ICC, IHC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Phospho-GSK3 (alpha + beta)(Y216 + Y279)
• Antibody Type: Recombinant Antibody
• Dilution range: WB:1:500~1:2000IHC:1:50~1:200ICC/IF:1:50~1:200IP:1:50
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Conjugation: Unconjugated
• MW: 51kDa/46kDa
• UniProt ID: P49840
• Source: Recombinant Rabbit
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of GSK3 alpha/ beta phosphorylation expression in 293 cell lysate treated with AP.