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GSK-3484862

SKU: orb1309609

Description

GSK-3484862 is a non-covalent, cell-active DNMT1 inhibitor that induces global DNA demethylation. It is a valuable chemical probe for epigenetic research in cancer biology and stem cell studies, demonstrating activity in both cellular and in vivo models.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number2170136-65-7
MW365.45
Purity>99.99% (May vary between batches)
FormulaC19H19N5OS
SMILESCCc1c(C#N)c(S[C@@H](C(N)=O)c2ccccc2)nc(N(C)C)c1C#N
TargetDNA Methyltransferase
SolubilityDMSO:22.5 mg/mL (61.57 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

5-Azacytidine, Dnmt1, DNMT1, DNMTs, DNA, DNA Methyltransferase, DNA MTases, DNAMethyltransferase, Inhibitor, inhibit, methyltransferase1, hypomethylation, GSK 3484862, GSK3484862, GSK-3484862, epigenetic, therapies

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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500 mg
100 mg
1 mg
$ 90.00
5 mg
$ 170.00
1 ml x 10 mM (in DMSO)
$ 180.00