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(Rac)-GSK-3484862

SKU: orb3218163

Description

(Rac)-GSK-3484862 is the racemic form of GSK-3484862, exhibiting very weak inhibitory activity against DNMT1, and can be used as a negative control for GSK-3484862. GSK-3484862 is a potent non-covalent inhibitor of the DNA methyltransferase DNMT1, exerting anticancer effects by inducing DNA hypomethylation and mediating global demethylation in mouse embryonic stem cells.

Images & Validation

Key Properties

CAS Number2170136-02-2
MW365.45
Purity98.93% (May vary between batches)
FormulaC19H19N5OS
SMILESN#CC1=C(N=C(C(C#N)=C1CC)N(C)C)SC(C(=O)N)C=2C=CC=CC2
TargetDNA Methyltransferase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

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1 mg
$ 90.00
5 mg
$ 180.00