GRK2i

SKU: orb1679324

Description

This polypeptide is a specific inhibitor of GRK2, functioning as a cellular Gβγ antagonist by mimicking its Gβγ-binding domain. It is a valuable tool for studying G protein-coupled receptor (GPCR) signaling pathways in both in vitro assays and in vivo models of cardiovascular and neurological research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: GRK
• CAS Number: 148505-03-7
• MW: 3484.08
• Formula: C₁₅₃H₂₅₆N₅₀O₄₁S
• SMILES: C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CCCNC(=N)N)=O)CCC3)CCCCN)=O)CC(N)=O)=O)CCCCN)=O)CCSC)=O)CCCCN)=O)CCC2)[C@H](C)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)[C@H](C)C)=O)CC(C)C)=O)CCC(N)=O)=O)CCC(N)=O)=O)C)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)=O)C)=O)CC(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCC(O)=O)=O)CCCCN)=O)CCCCN)=O)N)C=4C=5C(NC4)=CC=CC5

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90488863