Gramicidin A

SKU: orb1693737

Description

Gramicidin A is a hydrophobic peptide antibiotic from Bacillus brevis that forms cation-selective channels in lipid membranes. It exhibits antibacterial and antimalarial activity and has been shown in research to degrade HIF-1α, reducing tumor growth in xenograft models, making it a tool for studying ion transport and cancer biology.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 11029-61-1
• MW: 1882.29
• Formula: C₉₉H₁₄₀N₂₀O₁₇
• SMILES: CC(C)CC(NC(=O)C(C)NC(=O)CNC(=O)C(NC=O)C(C)C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCO
• Target: HIF|||Antibacterial|||Parasite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16170150