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Gramicidin A

SKU: orb1693737

Description

Gramicidin A is a hydrophobic peptide antibiotic from Bacillus brevis that forms cation-selective channels in lipid membranes. It exhibits antibacterial and antimalarial activity and has been shown in research to degrade HIF-1α, reducing tumor growth in xenograft models, making it a tool for studying ion transport and cancer biology.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Infectious Disease & Virology, Metabolism Research

Images & Validation

Key Properties

CAS Number11029-61-1
MW1882.29
FormulaC99H140N20O17
SMILESCC(C)CC(NC(=O)C(C)NC(=O)CNC(=O)C(NC=O)C(C)C)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCO
TargetHIF/HIF Prolyl-Hydroxylase,Antibacterial,Antibiotic,Parasite,HIF

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information