(-)-Epicatechin gallate

SKU: orb1305097

Description

(-)-Epicatechin gallate is a catechin isomer and potent antioxidant known to modulate membrane protein function. Its bilayer-modifying effects, studied using gramicidin A channels as probes, are linked to its gallate moiety, which can induce transient channel block. This compound is utilized in research on oxidative stress, membrane biophysics, and nutraceutical studies in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Neuroscience

Key Properties

• CAS Number: 1257-08-5
• MW: 442.37
• Purity: 99.93% (May vary between batches)
• Formula: C₂₂H₁₈O₁₀
• SMILES: O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@H]2[C@H](OC=3C(C2)=C(O)C=C(O)C3)C4=CC(O)=C(O)C=C4
• Target: Virus Protease,COX,Autophagy
• Solubility: H2O:2.5 mg/mL (5.65 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.04 mM);DMSO:131 mg/mL (296.13 mM)

Bioactivity

• Target IC50:
  COX-1:7.5 μM.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclooxygenase, COX, ( ) Epicatechin gallate, (-)-Epicatechin 3-gallate, (-)-Epicatechin 3-O-gallate, ()Epicatechin gallate, (−)-Epicatechin 3-gallate, Autophagy, Inhibitor, inhibit, Epicatechin 3-gallate, Epicatechin 3-O-gallate, Epicatechin gallate, ECG, Virus Protease, VirusProtease

Compound Identifiers

PubChem CID

107905