TBC1D9 Antibody

SKU: orb154570

Description

Goat polyclonal antibody to TBC1D9, which also known as MDR1 are thought to function as GTPase-activators for Rab proteins. It is a P-glycoprotein implicated in the mechanism of multidrug resistance to chemotherapeutic agents. TBC1D9 functions as an energy-dependent membrane efflux pump for lipophilic compounds.

Images & Validation

• Tested Applications: ELISA, WB
• Dilution Range: ELISA: 1:128000, WB: 0.3-1 μg/ml
• Reactivity: Human, Porcine
• Predicted Reactivity: Bovine, Canine, Mouse, Rat
• Application Notes:
  WB: Experiments gave bands at approx 90kDa and 55kDa in lysates of cell line HeLa. The sum of the observed sizes equals 145kDa. This protein has a calculated MW of 143kDa according to NP_055945.2. Recommended concentration: 0.3-1 μg/ml.

Key Properties

• Host: Goat
• Clonality: Polyclonal
• Target: TBC1D9
• Protein Sequence: EDKLHCEDIGEDT
• Molecular Weight: 143
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti TBC1D9 antibody, anti TBC1 domain family antibody, anti member 9 (with GRAM domain) antibody, anti TBC1 domain family member 9 antibody, anti TBC1 domain family member 9A antibody

Western blot analysis of staining of HeLa lysate using TBC1D9 antibody

Western blot analysis of staining of HeLa lysate using TBC1D9 antibody

Quick Database Links

Gene Symbol

TBC1D9

NCBI Gene ID

23158