Goat anti-MAP2K2 / MEK2 Antibody

SKU: orb154569

Description

Goat polyclonal antibody to MAP2K2 which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family. It highly expressed in the neonatal brain. It catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MAP2K2 activates the ERK1 and ERK2 MAP kinases. Genetic variation in MAP2K2 are a cause of cardiofaciocutaneous syndrome.

Research Area

Cell Biology

Images & Validation

• Tested Applications: ELISA, WB
• Dilution Range: ELISA: 1:128000, WB: 0.1-0.3 μg/ml
• Reactivity: Human
• Application Notes:
  WB: Approx 48kDa band observed in lysates of cell lines Daudi, Jurkat, K562 and Molt4 (calculated MW of 44.4kDa according to NP_109587.1). Recommended concentration: 0.1-0.3 μg/ml.

Key Properties

• Clonality: Polyclonal
• Target: MAP2K2 / MEK2
• Protein Sequence: DLKMLTNHTFIKRS
• Molecular Weight: 44,4
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti MAP2K2 antibody, anti mitogen-activated protein kinase kinase 2 antibody, anti MAPKK2 antibody, anti MEK2 antibody, anti MKK2 antibody, anti PRKMK2 antibody, anti ERK activator kinase 2 antibody, anti MAP kinase kinase 2 antibody, anti MAPK/ERK kinase 2 antibody, anti dual specificity mitogen-activated protein kinase kinase 2 antibody, anti mitogen-activated protein kinase kinase 2, p45 antibody

Quick Database Links

Gene Symbol

MAP2K2 / MEK2

NCBI Gene ID

5605