GNE Antibody

• Catalog Number: orb128120
• Category: Antibodies
• Description: Rabbit polyclonal antibody to GNE which is highly expressed in liver and placenta and also found in heart, brain, lung, kidney, skeletal muscle and pancreas. GNE has various functions like regulation and initiation of N- acetylneuraminic acid (NeuAc) biosynthesis, a precursor of sialic acids, which plays an essential role in early development and also required for normal sialylation in hematopoietic cells.
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human, Mouse, Rat
• Concentration: 1mg/ml
• Immunogen: C-terminal
• UniProt ID: Q9Y223
• Tested applications: IHC, WB
• Dilution range: WB: 1:500-1:3000, IHC-P: 1:50-1:100, ELISA: 1:5000
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: anti-Bifunctional UDP-N-acetylglucosamine 2-epimer
• Note: For research use only

References

Pawluczyk, Izabella Z. A. et al. Sialic acid attenuates puromycin aminonucleoside-induced desialylation and oxidative stress in human podocytes Exp Cell Res, 320, 258-268 (2014)

PubMed: 24200502

Western blot analysis of extracts from NIH/3T3 cells using GNE antibody

Immunohistochemical analysis of formalin-fixed and paraffin-embedded human placenta tissue using GNE antibody