Epstein-Bar Virus gH/gL Human Monoclonal Antibody (MALS verified)

SKU: orb3002160

Description

The Epstein–Barr virus (EBV) glycoproteins H (gH) and L (gL) form a heterodimer essential for viral entry into host cells. This complex mediates membrane fusion in cooperation with other viral glycoproteins, enabling EBV to infect both B lymphocytes and epithelial cells. Antibodies targeting gH/gL can block this fusion process, thereby neutralizing infection. Such antibodies are valuable tools for studying EBV pathogenesis, evaluating vaccine candidates, and developing diagnostic assays. Because gH/gL are conserved and exposed on the viral envelope, they elicit strong immune responses, making anti‑gH/gL antibodies important in both research and potential therapeutic applications.

Research Area

Infectious Disease & Virology; Immunology & Inflammation

Images & Validation

• Reactivity: Mouse

Key Properties

• Host: Human
• Clonality: Monoclonal
• Isotype: Human IgG1 | Human Kappa
• Clone No.: EBV
• Target: Glycoprotein H & Glycoprotein L/gH & gL (EBV)
• Source/Expression System: HEK293
• Purity: 0.95
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Powder
• Buffer/Preservatives: PBS, pH 7.4
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Glycoprotein H & Glycoprotein L/gH & gL (EBV)