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Catalog Number | orb1300908 |
---|---|
Category | Small Molecules |
Description | Givinostat hydrochloride |
CAS Number | 199657-29-9 |
Purity | 98% |
MW | 457.95 |
SMILES | Cl.CCN(CC)Cc1ccc2cc(COC(=O)Nc3ccc(cc3)C(=O)NO)ccc2c1 |
Formula | C24H28ClN3O4 |
Biological Activity | Givinostat hydrochloride (ITF2357 hydrochloride) is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat hydrochloride exhibits anti-inflammatory, anti-angiogenic, and antineoplastic activities. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.09% | |
732302-99-7 | |
475.97 | |
C24H30ClN3O5 |