Geminin / DNA Replication Inhibitor Antibody

• Catalog Number: orb1410078
• Category: Antibodies
• Description: Mouse monoclonal antibody to Geminin
• Target: GMNN
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: IgG1
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Immunogen: Recombinant fragment (around aa71-202) of human GMNN protein (exact sequence is proprietary)
• UniProt ID: O75496
• MW: 35kDa
• Tested applications: IHC
• Clone Number: GMNN/4033
• Expression System: CHO cells
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: DNA replication inhibitor; Gem; Geminin DNA replic
• Research Area: Cardiovascular Research, Cell Biology
• Note: For research use only

Analysis of Protein Array containing more than 19000 full-length human proteins using Geminin / DNA Replication Inhibitor Monoclonal Antibody (GMNN/4033). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human lymph node stained with Geminin Mouse Monoclonal Antibody (GMNN/4033).

Formalin-fixed, paraffin-embedded human testis stained with Geminin Mouse Monoclonal Antibody (GMNN/4033).

Formalin-fixed, paraffin-embedded human thymus stained with Geminin Mouse Monoclonal Antibody (GMNN/4033).

SDS-PAGE Analysis Purified Geminin Mouse Monoclonal Antibody (GMNN/4033). Confirmation of Purity and Integrity of Antibody.