GC Vitamin D Binding Protein Antibody

SKU: orb1410270

Description

Mouse monoclonal antibody to GC Vitamin D Binding Protein

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone No.: VDBP/4481
• Immunogen: Recombinant fragment (around aa 35-175) of human GC protein (exact sequence is proprietary)
• Target: GC
• Source/Expression System: Bioreactor
• Molecular Weight: 53kDa.
• Purification: Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

DBP/GC; Gc globulin; GRD3; Group specific component vitamin D binding protein; hDBP; VDB; VDBG; VDBP; Vitamin D binding alpha globulin; Vitamin D-binding protein

Analysis of Protein Array containing more than 19000 full-length human proteins using GC Vitamin D Binding Protein Mouse Monoclonal Antibody (VDBP/4481). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

IHC analysis of formalin-fixed, paraffin-embedded human pancreas. Staining using VDBP/4481 at 2 ug/ml in PBS for 30 min RT.

IHC analysis of formalin-fixed, paraffin-embedded human renal oncocytoma. Staining using VDBP/4481 at 2 ug/ml in PBS for 30 min RT. HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

SDS-PAGE Analysis of Purified GC Mouse Monoclonal Antibody (VDBP/4481). Confirmation of Purity and Integrity of Antibody.

Quick Database Links

Gene Symbol

GC

UniProt

P02774