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Catalog Number | orb1951585 |
---|---|
Category | Antibodies |
Description | This protein is associated with nerve growth. It is a major component of the motile growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.,,,,,1,,1,1,1,0,1,1701055481,0,0,0,0,0,0,0,1701055481,0,-1,-1,0,0 323585,57,58918,JAM1 Rabbit mAb,0,10,JAM1-Rabbit-mAb,JAM1 Rabbit mAb,,0,50ul,249,249,0,0,0,58,ABWAY,CY5635,CY5635,0,0,0,Yes,Rabbit Monoclonal Antibody,"Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. |
Species/Host | Rabbit |
Clonality | Recombinant |
Tested applications | FC, ICC, IHC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | A synthesized peptide derived from human GAP43 |
Antibody Type | Recombinant Antibody |
Dilution range | WB 1:10000~1:50000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:20 |
Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Conjugation | Unconjugated |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Alternative names | GAP43, Axonal membrane protein GAP-43, B-50, Growt Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature.
Immunohistochemical analysis of paraffin-embedded human stomach, using GAP43 Antibody.
Western blot analysis of GAP43 expression in SH-SY5Y cell lysate.