Gap 27

SKU: orb1296651

Description

Gap 27 is a synthetic peptide corresponding to residues 37-47 of connexin 43 (Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile). It functions as a selective inhibitor of gap junction communication. This tool compound is widely used in cardiovascular, cancer, and neurological research to study intercellular signaling in both in vitro and in vivo models.

Research Area

Signal Transduction

Key Properties

• Target: Gap Junction Protein
• CAS Number: 198284-64-9
• MW: 1304.53
• Purity: >99.99% (May vary between batches)
• Formula: C₆₀H₁₀₁N₁₅O₁₇
• SMILES: C([C@@H](NC([C@H](CO)N)=O)CCCNC(=N)N)(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)[C@H](CC)C)=O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CCCCN)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CCC1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, GapJunctionProtein, Gap 27, Gap Junction Protein, Gap27, Gap-27

Compound Identifiers

PubChem CID

9920128