Gamabufotalin

SKU: orb1302377

Description

Gamabufotalin (Gamabufagin), a key bufadienolide from Chansu, exhibits notable metabolic stability and a favorable safety profile. It is utilized in research for COX-2-mediated diseases and cancer therapy, demonstrating activity in both in vitro and in vivo experimental models.

Research Area

Cardiovascular Research, Immunology & Inflammation, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 465-11-2
• MW: 402.52
• Purity: 99.51%
• Formula: C₂₄H₃₄O₅
• SMILES: C[C@]12C[C@@H](O)[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@]34C)[C@@]1(O)CC[C@@H]2c1ccc(=O)oc1
• Target: COX,VEGFR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.97 mM);DMSO:25 mg/mL (62.11 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Gamabufagin, Gamabufotalin, inhibit, Inhibitor, COX-2, Vascular endothelial growth factor receptor, VEGFR

Compound Identifiers

PubChem CID

259803