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Catalog Number | orb386077 |
---|---|
Category | Antibodies |
Description | It recognizes a 32kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, LGALS13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, LGALS13 exists as a disulfide-linked homodimer. LGALS13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for LGALS13/Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | PP13/1165 |
Tested applications | ELISA, IHC-P |
Reactivity | Human |
Isotype | Mouse IgG2b, kappa |
Immunogen | A human partial recombinant protein corresponding to amino acids 23-134 was used as the immunogen for the LGALS13 antibody. |
Dilution range | ELISA (order BSA/sodium azide-free format for coating),Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT |
Purity | Protein G affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
Hazard Information | This LGALS13 antibody is available for research use only. |
UniProt ID | Q9UHV8 |
Storage | Store the LGALS13 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
Buffer/Preservatives | 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide |
Note | For research use only |
Application notes | Titering of the LGALS13 antibody may be required for optimal performance. |
Expiration Date | 12 months from date of receipt. |
Immunohistochemical staining of Human placenta using Galectin 13 antibody
FACS, IF, IHC-P, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
ELISA, IHC-P | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
ELISA, FACS, IF, IHC-P | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
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