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Galanthamine

SKU: orb1302305

Description

Galanthamine is a potent acetylcholinesterase inhibitor (IC50 ~500 nM) used in neuroscience research. It has demonstrated neuroprotective effects against hypoxic-ischemic brain injury in experimental models, supporting its application in studying cognitive disorders and neuroprotection mechanisms.

Research Area

Cell Biology, Neuroscience

Images & Validation

Key Properties

CAS Number357-70-0
MW287.35
Purity99.87% (May vary between batches)
FormulaC17H21NO3
SMILESCOc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24
TargetCholinesterase (ChE),Apoptosis
SolubilityDMSO:58.82 mg/mL (204.7 mM)

Bioactivity

Target IC50
AChE:500 nM
In Vivo
Galanthamine is a selective, reversible competitive acetylcholinesterase inhibitor that has been approved for the symptomatic treatment of Alzheimer's disease

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cholinesterase (ChE), AChE, Apoptosis, Inhibitor, inhibit, Galantamine, Galanthamine

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Galanthamine (orb1302305)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 90.00
50 mg
$ 90.00
100 mg
$ 110.00
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