G-quadruplex ligand 4

SKU: orb3175179

Description

G-quadruplexligand 4, a chromone derivative, functions as a human telomerase reverse transcriptase (hTERT) G4 ligand. It downregulates hTERT expression and exhibits significant cytotoxicity in triple-negative breast cancer (TNBC) cell lines. This compound induces S/G2 phase cell cycle arrest and apoptosis, while also downregulating the expression of hTERT, KRAS, and BCL-2. G-quadruplexligand 4 is utilized in research related to triple-negative breast cancer.

Key Properties

• Target: Bcl-2 Family,Apoptosis,Telomerase,DNA/RNA Synthesis,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Bcl-2 Family,Apoptosis,Telomerase,DNA/RNA Synthesis,Ras