G-Protein antagonist peptide

SKU: orb1679446

Description

This peptide, derived from Substance P, acts as a competitive and reversible inhibitor of G protein coupling to specific receptors. It blocks M2 muscarinic receptor-mediated activation of Gi/Go proteins and inhibits Gs activation by β-adrenoceptors. This tool is valuable for in vitro studies of G protein-coupled receptor (GPCR) signaling and cellular transduction pathways.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Adrenergic Receptor,AChR
• CAS Number: 143675-79-0
• MW: 1093.27
• Formula: C₅₇H₆₄N₁₂O₉S
• SMILES: C([C@H](C(N[C@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CCSC)C(N)=O)=O)=O)NC([C@@H](NC([C@@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC(=O)[C@H]5NC(=O)CC5)CCC(N)=O)=O)=O)CC6=CC=CC=C6)=O)C=7C=8C(NC7)=CC=CC8

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71308571