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Fz7-21

SKU: orb1219485

Description

Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2247635-23-8
MW1796.1
Purity>98% (HPLC)
FormulaC83H114N18O23S2
Targethuman FZD7 CRD|mouse FZD7 CRD

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Fz7-21 (orb1219485)

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Available Sizes

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200 mg
500 mg
5 mg
$ 420.00
10 mg
$ 610.00
25 mg
$ 980.00
50 mg
$ 1,370.00
100 mg
$ 1,840.00