Fz7-21

SKU: orb1219485

Description

Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2247635-23-8
• MW: 1796.1
• Purity: >98% (HPLC)
• Formula: C₈₃H₁₁₄N₁₈O₂₃S₂
• Target: human FZD7 CRD|mouse FZD7 CRD

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

human FZD7 CRD|mouse FZD7 CRD