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FXR agonist 14

SKU: orb3174496

Description

FXR agonist14 (Compound V15) is a partial, selective, orally active FXR agonist with an EC50 of 0.67 nM. It can ameliorate the pathological features in mice with MASH induced by a high-fat, high-sugar diet, and shows significant effects against cholestatic liver disease.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number3062988-46-6
MW568.66
FormulaC30H33FN2O6S
SMILESO=C(OCC)C1CCN(C(=O)CC2=CC=C(C=C2)N(CC=3C=CC=C(F)C3)S(=O)(=O)C=4C=CC=CC4OC)CC1
TargetFXR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information