FXR agonist 15

SKU: orb3174288

Description

FXR agonist15 is a selective, potent, orally active farnesoid X receptor (FXR) agonist with an EC50 of 0.76 μM. It does not significantly activate other nuclear receptors such as LXRα/β, PXR, PPARα/β/γ, and THR-β, with EC50 values exceeding 10 μM for each. FXR agonist15 is effective in alleviating symptoms like steatosis, lobular inflammation, hepatocellular ballooning, and liver fibrosis. It is applicable in research studies related to non-alcoholic steatohepatitis (NASH).

Key Properties

• CAS Number: 2991276-14-1
• MW: 526.4
• Formula: C₂₄H₂₂Cl₂FNO₅S
• SMILES: O=C(O)COC=1C=CC(=CC1F)C2=CC=C(C=C2)N(CC(C)C)S(=O)(=O)C=3C(Cl)=CC=CC3Cl
• Target: FXR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

FXR