Furanodienone

SKU: orb1302355

Description

Furanodienone is a bioactive small molecule that modulates key oncogenic pathways. It acts in part by inhibiting ERα signaling in MCF-7 breast cancer cells and selectively suppresses the HER2-dependent EGFR/HER2 pathway in HER2-positive cell lines like BT474 and SKBR3, making it a useful research tool for studying breast cancer mechanisms in vitro.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 24268-41-5
• MW: 230.3
• Purity: 99.91% (May vary between batches)
• Formula: C₁₅H₁₈O₂
• SMILES: Cc1coc2C\C(C)=C\CC\C(C)=C\C(=O)c12
• Target: EGFR,Apoptosis,HER
• Solubility: DMSO:22.5 mg/mL (97.7 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.68 mM)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, inhibit, HER2, Inhibitor, Furanodienone

Compound Identifiers

PubChem CID

6506548