FTO-IN-1

SKU: orb1298378

Description

UUN44923 is a potent and selective inhibitor of the fat mass and obesity-associated (FTO) demethylase. It serves as a valuable research tool for investigating the role of FTO in various diseases, including obesity, metabolic disorders, and specific cancers, in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2243944-92-3
• MW: 391.25
• Purity: 99.43% (May vary between batches)
• Formula: C₁₈H₁₆Cl₂N₄O₂
• SMILES: CC=1C(C2=CC(Cl)=C(NC3=C(C(NO)=O)C=CC=C3)C(Cl)=C2)=C(C)NN1
• Target: Others
• Solubility: Ethanol:80 mg/mL (204.47 mM);DMSO:1 mg/mL (2.56 mM)

Bioactivity

• Target IC50:
  FTO:<1 μM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cancer, associated, inhibit, obesity, Inhibitor, mass, fat, FTO IN 1, FTOIN1, FTO-IN-1, FTO, enzyme, UUN 44923, UUN44923, UUN-44923

Compound Identifiers

PubChem CID

152940130