Frentizole

SKU: orb1299738

Description

Frentizole is a small molecule immunosuppressive compound that specifically inhibits the interaction between amyloid-beta (Aβ) and the Aβ-binding alcohol dehydrogenase (ABAD). This inhibition has been investigated in vitro and in vivo for its potential to mitigate Aβ-induced mitochondrial dysfunction in Alzheimer's disease research.

Research Area

Neuroscience

Key Properties

• CAS Number: 26130-02-9
• MW: 299.35
• Purity: 99.82%
• Formula: C₁₅H₁₃N₃O₂S
• SMILES: COc1ccc2nc(NC(=O)Nc3ccccc3)sc2c1
• Target: Beta Amyloid
• Solubility: DMSO:3 mg/mL (10.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.34 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

bAmyloid, Aβ-ABAD, b Amyloid, Amyloid-β, amyloid-β, Abeta, Beta Amyloid, BetaAmyloid, Frentizole, immunosuppressant, Inhibitor, inhibit, rheumatoid arthritis, systemic lupus erythematosus, β-amyloid peptide, βAmyloid, β Amyloid

Compound Identifiers

PubChem CID

33334