Fraxinellone

SKU: orb1300270

Description

Fraxinellone is a bioactive small molecule with demonstrated anti-inflammatory effects in murine colitis models and broad insecticidal activity. Its mechanisms include disrupting midgut metabolism in pests like Mythimna separata by modulating key enzymes such as proteases, carboxylesterases, and glutathione S-transferases.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 28808-62-0
• MW: 232.27
• Purity: 99.92% (May vary between batches)
• Formula: C₁₄H₁₆O₃
• SMILES: [H][C@]1(OC(=O)C2=C(C)CCC[C@@]12C)c1ccoc1
• Target: STAT,HIF/HIF Prolyl-Hydroxylase,PD-1/PD-L1
• Solubility: DMSO:42 mg/mL (180.82 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.61 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, HIFProlylHydroxylase, HIFs, HIF-PH, HIF/HIFProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF, Hypoxia-inducible factors, Fraxinellone, PDL1, PD-L1, PD1, PD-1, PD1/PDL1, PD-1/PD-L1, inhibit, STAT

Compound Identifiers

PubChem CID

124039