Frataxin Antibody / FXN

• Catalog Number: orb639667
• Category: Antibodies
• Description: Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
• Species/Host: Mouse
• Clonality: Recombinant
• Clone Number: rFXN/2124
• Tested applications: ELISA
• Reactivity: Human
• Isotype: Mouse IgG1, kappa
• Immunogen: Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody.
• Antibody Type: Primary Antibody
• Dilution range: ELISA (order BSA-free format for coating)
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This recombinant Frataxin antibody is available for research use only.
• UniProt ID: Q16595
• Storage: Store the recombinant Frataxin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.

SDS-PAGE analysis of purified, BSA-free recombinant FXN antibody (clone rFXN/2124) as confirmation of integrity and purity.