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Catalog Number | orb639667 |
---|---|
Category | Antibodies |
Description | Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet. |
Clonality | Recombinant |
Species/Host | Mouse |
Isotype | Mouse IgG1, kappa |
Conjugation | Unconjugated |
Reactivity | Human |
Immunogen | Amino acids 57-210 from the human protein were used as the immunogen for this FXN antibody. |
UniProt ID | Q16595 |
Tested applications | ELISA |
Dilution range | ELISA (order BSA-free format for coating) |
Application notes | Optimal dilution of the antibody should be determined by the researcher. |
Antibody Type | Primary Antibody |
Clone Number | rFXN/2124 |
Formula | 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Hazard Information | This recombinant Frataxin antibody is available for research use only. |
Note | For research use only |
SDS-PAGE analysis of purified, BSA-free recombinant FXN antibody (clone rFXN/2124) as confirmation of integrity and purity.