Flunixin meglumine

SKU: orb1309402

Description

Flunixin meglumine (Banamine) is a potent cyclooxygenase (COX) inhibitor, exhibiting anti-inflammatory and antipyretic properties. It is widely used in veterinary and biomedical research for studying inflammation and pain mechanisms in both in vivo animal models and in vitro cellular assays.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 42461-84-7
• MW: 491.46
• Formula: C₂₁H₂₈F₃N₃O₇
• SMILES: CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
• Target: COX
• Solubility: DMSO:50 mg/mL (101.74 mM);H2O:90 mg/mL (183.13 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.07 mM);Ethanol:8 mg/mL (16.28 mM)

Bioactivity

• Target IC50:
  COX-1:17 nM (IC50)|COX-2:0.4 nM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Flunixin, Flunixin meglumin, Flunixin meglumine, Finadyne, Banamine, anti-inflammatory effect, Cyclooxygenase, COX-1, COX-2, COX, RAW 264.7 murine macrophages

Compound Identifiers

PubChem CID

39212