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FLT3-ITD-IN-2

SKU: orb2814678

Description

FLT3-ITD-IN-2 (Compound A1) is a potent and selective FLT3-ITD kinase inhibitor with an IC50 of 2.12 nM. It inhibits proliferation of MOLM-13 AML cells (IC50=25.65 nM) and demonstrates antitumor activity in acute myeloid leukemia research models, supporting its use in both in vitro and in vivo studies.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

MW726.86
FormulaC39H50N8O6
TargetFLT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

FLT3-ITD-IN-2 (orb2814678)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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