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FGFR4-IN-1

SKU: orb1296095

Description

FGFR4-IN-1 is a highly potent and selective fibroblast growth factor receptor 4 inhibitor with an IC50 of 0.7 nM. This compound is a valuable chemical probe for investigating FGFR4 signaling in cancer research, supporting both in vitro biochemical assays and in vivo studies targeting FGFR4-driven malignancies.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1708971-72-5
MW493.52
Purity98.96% (May vary between batches)
FormulaC24H27N7O5
SMILESCOCCNc1cc(NC(=O)N2CCCc3cc(CN4CCOCC4=O)c(C=O)nc23)ncc1C#N
TargetFGFR
SolubilityDMSO:6 mg/mL (12.16 mM)

Bioactivity

Target IC50
FGFR4:0.7 nM
In Vitro
FGFR4-IN-1 inhibits the proliferation of hepatocellular carcinoma cells HuH-7 (IC50: 7.8 nM).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, FGFR4, FGFR4 IN 1, FGFR4IN1, FGFR-4-IN-1, FGFR4-IN-1, FGFR, Fibroblast growth factor receptor, Inhibitor

Similar Products

  • FGFR4-IN-1 [orb1218647]

    >98% (HPLC)

    1708971-72-5

    493.52

    C24H27N7O5

    2 mg, 5 mg, 10 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 90.00
5 mg
$ 140.00
1 ml x 10 mM (in DMSO)
$ 140.00
10 mg
$ 200.00