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FGFR4-IN-1

SKU: orb1218647

Description

FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number1708971-72-5
MW493.52
Purity>98% (HPLC)
FormulaC24H27N7O5
SMILESCOCCNc1cc(NC(N2c3nc(C=O)c(CN(CCOC4)C4=O)cc3CCC2)=O)ncc1C#N
TargetFGFR
SolubilityDMSO:6 mg/mL (12.16 mM; Need warming)

Bioactivity

In Vitro
FGFR4-IN-1 significantly inhibits the proliferation of HuH-7 hepatocellular carcinoma cells with IC50 of 7.8 nM.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • FGFR4-IN-1 [orb1296095]

    98.96% (May vary between batches)

    1708971-72-5

    493.52

    C24H27N7O5

    5 mg, 10 mg, 25 mg, 1 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

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100 mg
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$ 120.00
5 mg
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