FGFR1/DDR2 inhibitor 1

SKU: orb1218368

Description

FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.

Key Properties

• CAS Number: 2308497-58-5
• MW: 501.5
• Purity: >98% (HPLC)
• Formula: C₂₈H₂₂F₃N₅O
• SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=C(C=C3)C(=NN4)C5=CN(N=C5)C6CC6
• Target: FGFR
• Solubility: DMSO:250 mg/mL (498.50 mM; Need ultrasonic);H2O:< 0.1 mg/mL (insoluble)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

FGFR