FCGR1A Antibody / CD64

• Catalog Number: orb639653
• Category: Antibodies
• Description: Three different classes of IgG Fc receptors have been described: Fc stimulation. CD64 plays a putative role in the initiation of cell-mediated cytotoxicity. Thus far, three genes encoding four distinct CD64 transcripts have been described. CD64 has been shown to associate with signal transducing subunit of the high affinity IgE receptor. Src family kinases Hck and Lyn show increased kinase activity and will co-immunoprecipitate with CD64 subsequent to receptor cross linking.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 10.1
• Tested applications: FACS
• Reactivity: Human
• Isotype: Mouse IgG1, kappa
• Immunogen: Rheumatoid synovial fluid cells and human monocytes were used as the immunogen for the CD64 antibody.
• Dilution range: Flow cytometry: 1-2ug/million cells
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This CD64 antibody is available for research use only.
• UniProt ID: P12314
• Storage: Store the CD64 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.