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FBW7 (N) Antibody, Rabbit Polyclonal
Catalog Number: orb67185
| Catalog Number | orb67185 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to FBW7.F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination andsubsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds tophosphorylated target proteins. FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1released notch intracellular domain (NICD), and probably PSEN1. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human |
| Immunogen | N-terminal region of human DDB1 |
| Dilution range | WB:1:1000-1:3000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 80 |
| UniProt ID | Q969H0 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-FBW7 antibody,anti-Fbox antibody,anti-WD repe Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela(Lane1) and human T47D(Lane2) using FBW7 antibody
