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FAK inhibitor 7

SKU: orb2665199

Description

FAK inhibitor7 is a potent small molecule (IC50 = 3.58 nM) targeting focal adhesion kinase. It blocks downstream Src/AKT signaling, inducing G0/G1 arrest and cytotoxic autophagy in ovarian cancer cells in vitro, and inhibits tumor growth and metastasis in mouse models in vivo.

Research Area

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2890814-94-3
MW567.68
FormulaC32H37N7O3
SMILESO=C1C=2C(OC3=NC(=NC=4NC=CC34)NC5=CC=C(C=C5OC)N6CCC(N7CCN(C)CC7)CC6)=CC=CC2CC1
TargetAutophagy|||Src|||FAK|||Akt

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information