FABP7 Antibody (brain)

SKU: orb248161

Description

Fatty acid binding proteins (FABPs) are proteins that bind long-chain fatty acids and are thought to be involved in fatty acid uptake, transport, and metabolism. FABP7, also known as Brain lipid binding protein or BLBP, is essential for fetal brain development, and has been found to be important in brain and breast cancer, with opposing prognoses. It is a glioblastoma stem cell marker, highly expressed in the astrocyte-derived tumor cells and an indicator of poor prognosis. Abundant expression in basal-like/triple negative (ER-, PR-, HER2-) breast cancer cells, particularly with only nuclear expression, indicates a positive prognosis.

Images & Validation

• Tested Applications: WB
• Dilution Range: Western blot: 2-5ug/ml
• Reactivity: Human, Mouse, Primate, Rat
• Application Notes:
  Provided assay concentrations are suggestions only, FABP7 antibody titration may be required for optimal results.

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: A recombinant protein fragment from the C-terminal region of FABP7 was used as the immunogen for this antibody.
• Purification: Protein A Affinity Chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Western blot testing of human samples with FABP7 antibody at 2 ug/ml. U87 is a human glioma tumor cell line.