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FABP4 Antibody / Fatty Acid Binding Protein 4

Catalog Number: orb2635514

DispatchUsually dispatched within 5-10 working days
$ 410.00
Catalog Numberorb2635514
CategoryAntibodies
DescriptionFatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21.13, and encodes a 132 amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue.
Species/HostMouse
ClonalityMonoclonal
Clone NumberFABP4/4423
Tested applicationsIHC-P
ReactivityHuman
IsotypeMouse IgG1, kappa
ImmunogenA portion of amino acids 1-132 was used as the immunogen for the FABP4 antibody.
Antibody TypePrimary Antibody
Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml
ConjugationUnconjugated
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Hazard InformationThis FABP4 antibody is available for research use only.
UniProt IDP15090
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NoteFor research use only
Application notesOptimal dilution of the FABP4 antibody should be determined by the researcher.
Expiration Date12 months from date of receipt.
FABP4 Antibody / Fatty Acid Binding Protein 4

Analysis of HuProt (TM) microarray containing more than 19000 full-length human proteins using FABP4 antibody (clone FABP4/4423). These results demonstrate the foremost specificity of the FABP4/4423 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

FABP4 Antibody / Fatty Acid Binding Protein 4

IHC staining of FFPE human placental tissue with FABP4 antibody (clone FABP4/4423). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

FABP4 Antibody / Fatty Acid Binding Protein 4

IHC staining of FFPE human placental tissue with FABP4 antibody (clone FABP4/4423) at 2 ug/ml. Negative control inset: PBS instead of primary antibody to control for secondary binding. HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

  • FABP4 Antibody / Fatty Acid Binding Protein 4 [orb2635513]

    IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg
  • FABP4 Antibody / Fatty Acid Binding Protein 4 [orb2635515]

    IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg